Sharp gastroduodenit – the sharp inflammatory process affecting a mucous membrane of a stomach (pilorichesky department) and a duodenum. It is shown by appetite loss, nausea, vomiting, the dispepsichesky phenomena. For the purpose of diagnostics of a sharp gastroduodenit apply an ezofagogastroduodenoskopiya with a biopsy, a stomach X-ray analysis, various methods of identification H.pylori, an antroduodenalny manometriya, an elektrogastrografiya. Treatment includes a balanced diet, an eradikation of infectious agents (H.pylori, parasites), antisekretorny medicines and drugs for motility correction, symptomatic therapy.
Sharp gastroduodenit – one of the most widespread gastroenterologichesky pathologies as the instruction on this disease in the anamnesis is available practically for each adult inhabitant of the planet. Gastroduodenit is one of kinds of sharp gastritis when inflammatory process extends from a stomach to a mucous membrane of DPK. Feature of this disease is that a third of patients have at all no clinical manifestations (or the disease proceeds in the latent form), and at the others only tool methods allow to verify localization of inflammatory process. Men ask for medical care with this diagnosis three times more often than women. To reveal gastroduodenit can at any age, however the frequency of transition of a disease to a chronic form over the years increases.
Reasons of a sharp gastroduodenit
Sharp gastroduodenit is a multifactorial disease, and its development requires simultaneous influence of several pathological agents. All factors are divided into two groups: internal and external. Refer strengthening of formation of acid in a stomach to the internal reasons of formation of a sharp gastroduodenit, oppression of a slizeobrazovaniye, failure of hormonal regulation of digestion and violation of work of a liver and biliary tract owing to their pathology. Rank an invasion of infectious and parasitic agents as the external reasons (H.pylori, lyambliya, a cytomegalovirus), influence of various chemical and physical factors (food temperature, hot dishes, pesticides and other aggressive substances, alcohol).
Influence of internal pathological factors usually leads to weakening of protective mechanisms in a mucous membrane of a stomach and DPK that creates favorable conditions for development of the inflammatory process caused by external factors. Inflammatory process can progress, leading to emergence in a mucous membrane of erosive and ulcer changes. Untimely diagnostics of this state, irrational treatment can end with transition of a disease to a chronic form.
In spite of the fact that gastritis also duodenit in many classifications are considered as two separate diseases, actually they have much in common and extremely seldom develop separately. Because of the general etiology and pathogenesis of these nosological units included such concept in classification as gastroduodenit. Influence of aggressive pathological factors exerts impact not only on a mucous membrane of a stomach, but also on a duodenum, and the remaining sharp gastritis supports inflammatory process in DPK.
Sharp gastroduodenita divide on primary (are caused by external factors) and secondary (develop under the influence of the internal reasons, other diseases); extended and localized; with the kept or changed secretion of a stomach (increased lowered); separately allocate rare species of sharp gastroduodenit (for example, Cytomegaloviral). By results of an endoscopic research distinguish sharp gastroduodenit catarrhal (superficial), ulcer and erosive, with prevalence of atrophic or hyper plastic processes. Histologic studying of bioptat allows to define such changes at a sharp gastroduodenit: inflammation of easy, moderate, heavy degree; atrophy of a mucous membrane, intestinal metaplaziya.
Symptoms of a sharp gastroduodenit
Emergence of clinical signs of a sharp gastroduodenit is usually accurately connected with influence of an etiologichesky factor: literally in several hours after an overeating, the uses of low-quality food, alcohol of people feels strong weakness, dizziness, nausea. Skin becomes pale, cold, the patient can show complaints to a shiver in fingers, heartbeat, temperature increase. After a while nausea passes into vomiting with the eaten food with slime impurity, sometimes with blood streaks. Also quite often at height of a disease there is a diarrhea which in the future is replaced by locks. It is necessary to pay attention that the combination of nausea, weaknesses and dizzinesses at a sharp gastroduodenit is often treated as a sign of defeat of TsNS, leads to late diagnosing of inflammatory process of a GIT and deterioration in a condition of the patient.
Pain at a sharp gastroduodenit usually arises suddenly, initially settling down in the top half of a stomach, and then in an epigastriya and the left podreberye. The expressed pain syndrome at a sharp gastroduodenit is connected with hypostasis of a mucous membrane of DPK because of what work of smooth muscles of a small intestine will be paralyzed, swells fater of pacifiers and evacuation of bile and pancreatic juice from biliary tract is broken. In emergence of a pain syndrome stretching of the inflamed stomach and duodenum the food masses, digestive juice is of also great importance. Easing of pain in situation on cards, on the left side is characteristic of a sharp gastroduodenit. Unlike an exacerbation of stomach ulcer, reception of antatsid at a sharp gastroduodenit does not render soothing effect.
Heartburn disturbs men of young age more often, and its emergence is not connected with change of acidity of a stomach, and caused by hyper secretion of its mucous. Diarrhea is connected with hyperproduction of digestive juice in the inflamed duodenum, and also the accompanying damage of a pancreas. To emergence of such symptoms as weakness, dizziness, a headache, a tremor of fingers of hands, heartbeat and pains in heart give the hormonal and reflex frustration connected with the expressed inflammatory process in a stomach and DPK, organism intoxication.
Diagnostics of a sharp gastroduodenit
A variety of the symptoms characteristic of many diseases of a gastrointestinal tract leads to what the diagnosis sharp gastroduodenit not always can be verified at the first survey of the patient. Besides, as it was already told above, the nausea combination to signs of damage of the central nervous system can lead to the unreasonable direction of the patient to the neurologist and other profile experts. Consultation of the gastroenterologist in all disputable cases will help to expose quickly the correct diagnosis and in due time to begin treatment.
In diagnostics of a sharp gastroduodenit consultation of the endoscopist has the main role. Competently carried out ezofagogastroduodenoskopiya with an endoscopic biopsy of a mucous membrane, a morphological research of bioptat will allow to define degree and prevalence of inflammatory process (gastritis, bulbit), the nature of changes in a mucous membrane (proliferative or atrophic). As in emergence of a sharp gastroduodenit H.pylori invasion matters, various techniques of its identification are used: definition a helikobakter in Calais by IFA method, PTsR-diagnostics, definition of antibodies to a helikobakter in blood, the respiratory test.
Functions of a stomach and duodenum allow to define extent of violation motor such researches as a stomach X-ray analysis with use of a baric suspension, an elektrogastrografiya, an antroduodenalny manometriya. The intragastric rn-metriya gives the chance to reveal violations of secretion of hydrochloric acid in a stomach (in other words whether sharp proceeds gastroduodenit with the normal, increased or lowered secretion). The conducted complex of endoscopic and histologic researches allows to differentiate sharp gastroduodenit with stomach ulcer of a stomach and DPK, dyspepsia of functional character.
Treatment of a sharp gastroduodenit
The heavy current of a sharp gastroduodenit can demand hospitalization of the patient in office of gastroenterology. Today purpose of any certain diet is considered unreasonable, it is only recommended to eat rationally and to avoid products which can cause deterioration in a state. If in the course of inspection infectious agents (staphylococcus, a helikobakterny infection, parazitoza) are revealed, antibacterial or anti-parasitic therapy is appointed.
If the research of sekretorny function of a stomach revealed the increased acidity of gastric juice, or the helikobakterny infection was authentically verified, blockers of a proton pomp, H2-histamine receptors are used. If secretion of hydrochloric acid is considerably reduced, in treatment hydrochloric acid can be used. Also motility modulators are used: , . Symptomatic medicines can add etiopatogenetichesky therapy: spazmolitik, a probiotics, medicines for treatment of diarrhea, vitamin complexes etc.
Forecast and prevention of a sharp gastroduodenit
The forecast at a sharp gastroduodenit in general favorable, however you should not forget about possible transition of a disease to a chronic form. For the prevention of a sharp gastroduodenit it is necessary to eat, refuse rationally smoking and alcohol, to avoid stresses. It is also necessary to have annually routine inspections at the therapist for timely detection of a helikobakterny infection.