Atrofodermiya – the skin atrophy option including a number of diseases which cornerstone degenerate and atrophic processes in epidermis and a term are. The disease possesses a tendency to a long current, has no gender component, out-of-season. The clinic of each pathology entering into group of an atrofodermiya is specific; common feature is education on integuments of the atrophic centers. In diagnostics crucial importance belongs to a histologic research of a bioptat of skin. Treatment symptomatic (vitamin therapy, fizio-and balneoterapiya), forecast favorable. During an atrofodermiya there is an oncological vector.
Atrofodermiya – several seldom found chronic pathologies having a complex of the dystrophic changes of skin which are intermediate between a classical atrophy of skin and a classical sklerodermiya in the basis. They can be congenital and acquired, symptomatic or to act as an independent disease. The reasons and the mechanism of development of an atrofodermiya are a dermatology object of research throughout century, but up to the end are not found out and today. For example, the worm-shaped atrofodermiya was described at the end of the XIX century when studying a follicular keratoz of eyebrows (a nadbrovny eritema of Unn) as an outcome of this disease. The mesh atrofodermiya is known under the name of a poykilodermiya of Jacobi since 1906 (a mesh eritematozny atrofodermiya of Müller, an eritematozno-atrophic poykilodermiya of Milian — Perena, atrophic dermatitis of Gluck, Thomson's syndrome, Rotmund's syndrome). The limited atrofodermiya of Pazini-Pyerini is for the first time described in 1875, and a neurotic atrofodermiya - in 1864 by the English surgeon Pedzhet.
The clinical picture of an atrofodermiya in each separate case has the features. As precisely the etiology of a disease is not established, treatment symptomatic. Relevance is connected with a possibility of regeneration of poykilodermichesky process in a malignant new growth.
Atrofodermiya arises because of violation of food of all layers of skin as a result of definitely not established reasons. Dermatologists consider that vascular frustration - a zapustevaniye, narrowing of a gleam of the vessels nourishing skin - neuroendocrine or infectious and toxic character (radiation exposure, Ural federal district, a system dermatosis) are the cornerstone of a mesh atrofodermiya (poykilodermiya).
The worm-shaped atrofodermiya appears owing to change traffic of skin, destruction of its glands because of endocrine and vegetative frustration (vitamin A synthesis violation, diabetes). The Neyrotichesky atrofodermiya – result of violations in central and peripheral nervous the systems leading to disorder of exchange processes (polyneuritis, injury of a nerve). The limited atrofodermiya of Pazini-Pyerini has in the basis a combination of all above-mentioned reasons against the background of sharp easing of the general and local immunity.
Classification of an atrofodermiya
Classification of an atrofodermiya is more likely quantitative interpretation of the diseases entering into its group. Distinguish:
- Atrofodermiya worm-shaped – a disease of young people, a basic element is the follicular stopper symmetrized on cheeks from the outcome in a small atrophic scar. Such mesh "izjedennost" of skin reminds bark of a tree or honey honeycombs.
- Atrofodermiya idiopathic Pazini-Pyerini – a rare disease, strikes mainly young women. It is localized on a trunk. Primary element - the oval spot which is sinking down in the center which is transformed to a plaque, and then to the limited center of an atrophy.
- Atrofodermiya neurotic – is surprised skin of extremities, is broken a traffic of fabrics with the advent of the atrofo-dystrophy centers, thinning of nails and a hair loss.
- Atrofodermiya mesh (poykilodermiya) – a disease out of age and a floor. It is localized most often on open sites of skin in the form of an eritema from the outcome in the pigmented atrophy center.
The clinic of an atrofodermiya is individual for each disease entering into group of this pathology. The worm-shaped atrofodermiya has the most characteristic clinical picture: young people on cheeks have symmetrized small (1-3 mm), sinking-down defects of skin of fancy outlines up to 1 mm in depth. These are the deformed follicles filled, as a rule, with grease traffic jams. They merge, form crossed "waves", "lines", "cells" which, together with sites of normal skin between them remind the drawing of bark of a tree, corroded worms, or honey honeycombs. With age symptoms smooth out.
The clinic of an idiopathic form reminds the limited center of a superficial sklerodermiya, it is pressed into surrounding healthy skin, the small size (to 2 cm), an oval form, soft at a palpation, corporal color, single or multiple, tends to merge to formation of scalloped forms. Settles down on a stomach or a back.
The neurotic form is characterized by damage of fingers of hands and legs: skin shines, is strained, apparently, that when bending a brush or foot it "will burst", integuments get a cyanotic shade, as at an akrotsianoza, because of insufficient capillary blood supply. Over time, food of this site of skin practically stops, it becomes deathly pale, becomes thinner, in the center of an atrophy transparent nail plates and a hair loss are observed.
Poykilodermiya, or a mesh atrofodermiya, settles down on open sites of skin, in a decollete zone. Visually looks as the spotty surface of skin because of alternation of the atrophic, pigmented spots with depigmented. Transformation in a melanodermiya, fungoid mycosis is possible.
Diagnostics and treatment of an atrofodermiya
The atrofodermiya on the basis of clinical manifestations and results of histologic researches is diagnosed. The Potomorfologichesky picture of each pathology is individual. Differentiate a disease with parapsoriasis, a sklerodermiya, dermatmiozity, beam dermatitis, fungoid mycosis, melanozy, keratozy Siemens, Bazeks's syndrome, nadbrovny ulyeritemy, chicken pox, vulgar eels. A basis of differential diagnostics - clinic in combination with results of a biopsy of skin.
Treatment consists in sanitation of the centers of a chronic infection, first of all, of tuberculosis, syphilis. Effective therapy is necessary it is long the existing somatic diseases (diabetes, diseases of a thyroid and parathyroid gland, rheumatism, obesity). Symptomatic apply vitamin therapy (vitamin A, outwardly and inside, polyvitamins), the means improving to a traffic of fabrics (), iron medicines, diazepam. Thermal procedures, a dermabraziya, bathtubs with bran, sea, radonic bathtubs are effective; mud cure (the Crimea, Naftalan), massage and exercises for improvement of food of skin.
Prevention of an atrofodermiya consists in a priority of a healthy lifestyle. The forecast is favorable for life. At a poykilodermiya obligatory observation at the dermatologist because of a possibility of regeneration in is necessary.